Hello, I'm not a bot and I am not using the AI assistant to write this bid..
I am a Software Engineer and I want to help you.
Wow, your project description its pretty consistent and descriptive, but I didn't understand something, could you confirm me please, do you want to process the audio or do you want to control the device from the USB serial COM port to send and receive commands then handle the device?
I am a hardware guy, so I can control any device through the serial port if I have the right communication protocol using Python.
Also, I see you want to control multiple devices, so I could suggest you to switch to Linux instead of Windows, it's more stable, my suggestion, use a Raspberry instead. If you want to use windows because your main program is in there or something like that, then we can redirect the data from your third party application to the Raspberry, then control the devices, also the web page could be hosted in the pi.
Anyway, I'm sure there is more to be discussed.
EDIT:
I just saw your clarification board, I can't develop a rich GUI like the one you sent. But for the backend of course yes.
If this sounds interesting to you, then contact me.
Waiting for your comments.
Thanks
Martin O.
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If we decide to work together, your project will be guaranteed to be 100% completed, I have all the skills and tools to achieve it.